The computational genomics group is a joint initiative by five independent research groups whose principal investigators (PIs) are affiliated to the Universitat Pompeu Fabra and that carry out research in different areas of molecular biology using computational methods.

The five research groups and their PIs are:

Genome Bioinformatics group Roderic Guigó (CRG,UPF,IMIM)
Evolutionary genomics group Mar Albà (ICREA,FIMIM,UPF)
Regulatory genomics group Eduardo Eyras (ICREA,UPF)
Biomedical genomics group Núria Lopez-Bigas (UPF)
Functional genomics group Robert Castelo (UPF)